Folio (415 x 270 mm.), [6] ff., 824 pages, [24] ff., including two pages with folding extensions, woodcut title, portrait of Vesalius, about 200 woodcuts anatomical illustrations in the text, and printer’s device on verso of last leaf. 18th century half calf.

Second folio edition of one of the most important books in the history of medicine, the foundation of modern anatomy and physiology. “Containing Vesalius’ s final revisions of the text, this edition is also superior for its enlarged format, improved typography and printing, better paper, larger woodcut initials, and changes to the lettering of the anatomical woodcuts.”(Garrison-Morton)
“No other work of the sixteenth century equals it, though many share its spirit of anatomical enquiry. It was translated, reissued, copied and plagiarized over and over again and its illustrations were used or copied in other medical works until the end of the eighteenth century.”(PMM)

Garrison-Morton 377; Durling 4579; PMM 71.